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Showing posts from May, 2020

Unintentional Losses in our Life!

Unintentional Losses in our Life! 1 Samuel 9:3 – “ now the donkeys of Kish, Saul’s father were lost.   So kish told Saul his son, “ take one of the young men with you, arise and go and look for the donkey” Sometimes, we might be so heartbroken by the losses of our lives. The hardships we would have been through, when gets shattered in a day or less, our mind may even question the creator. In all these situations, we might blame ourselves or our friends or kins. We fail to recognize the plan, Lord has for this very loss / failure that we are in. This entire chapter 9 and 10 reveals us the hard ways   laid forward by our   creator to bring his plans in our life.    This is the first verses in the   bible about king Saul’s life.   It starts from a loss in   his   life. Yes. They lost their donkey and Saul is supposed to get it back for his father. When we read   1 Samuel 9:16- we realize that on the day before this incident, Lord had already instructed Prophet Samuel

Investigations for cushing's syndrome- A systematic approach

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Investigations for cushings syndrome Dr. Sanoop Kumar Sherin Sabu In the background of clinical feature of cushings, after ruling out exogenous intake of steroids,   we have the following important investigations to be done systematically to reach to the correct cause for features of cushings. ·          24 hour urine free corrtisol excretion ·          Midnight corrtisol ·          8 am corrtisol ·          1mg Dexa suppression test ·          Low dose dexa suppression test ·          High dose dexa suppression test ·          CRH responsiveness ·          Inferior petrosal sinsus sampling ·          Chest xray ·          MRI brain ·          Plain/ CECT abdomen   To understand the above investigations we should know:- ·          Why is the test done for ·          What is the physio-anatomical basis Causes of cushings syndrome –   Exogenous steroid intake>> ACTH dependant> ACTH independent ACTH dependant ACTH independant